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KMID : 1161420200230050485
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Journal of Medicinal Food
2020 Volume.23 No. 5 p.485 ~ p.490
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Effervescent Glutamine Formulation Improves the Beneficial Effects of Antiretroviral Therapies on Immune Function in HIV/AIDS Carrier Patients
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Krupek Tuane
Ferrari Bruna Juliana Wanczinski
da Silva Maria Angelica Raffaini Covas Pereira
Schamber Christiano Rodrigues
Bertolini Dennis Armando
Bruschi Marcos Luciano
Previdelli Isolde Terezinha Santos
Pereira Omar Cleo Neves
Dias Jose Ricardo Colleti
Curi Rui
Bazotte Roberto Barbosa
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Abstract
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The impact of oral supplementation with an effervescent glutamine formulation on the beneficial effects of antiretroviral therapies was evaluated in people living with HIV/AIDS. For this purpose, 12 HIV/AIDS carrier patients with CD4+ T cell counts <500, and who had received the same antiretroviral therapy for at least 1 year before starting this investigation were selected. The patients were required to dissolve the effervescent glutamine formulation (supplied in sachets) in water immediately before oral ingestion (12.4?g), once a day, after lunch or after dinner during 30 days. CD4+ T cell counts, complete blood cell counts, serum cytokines, and amino acids levels were quantified; biochemical and toxicological measurements were performed. The numbers of CD4+ T cells were increased (P?
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KEYWORD
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CD4+ T cell, cytokines, effervescent formulation, inflammation, nutraceuticals
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